Heart disease causes scar formation in the heart and pathological changes in the cardiac autonomic nervous system, which predispose to abnormal heart rhythms, including atrial and ventricular arrhythmias, and heart failure. The Vaseghi lab focuses on identifying the mechanisms and triggers for this neural remodelling and finding ways to prevent arrhythmias and reduce progression of heart failure by exploring a variety of neuromodulatory approaches.
Dr. Vaseghi is a cardiologist, clinical cardiac electrophysiologist, and Director of Clinical and Translational Research at the UCLA Cardiac Arrhythmia Center. She obtained her MD from Stanford University and her PhD in Molecular, Cellular, and Integrative Physiology at UCLA. She is the principle investigator and co-investigator of several National Institute of Health funded studies evaluating the role of autonomic nervous system in heart rhythm disorders and the development and role of new neuromodulatory therapies as well as catheter ablation techniques to treat arrhythmias. She is the recipient of the NIH New Innovator Award. Her laboratory’s breadth of work ranges from small and large animal models to human mechanistic studies to study cardiac autonomic innervation.
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