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American College of Cardiology Scientific Sessions, 2024
The β1-selective blocker metoprolol does not improve vagal function in the setting of healthy or structurally diseased hearts.
van Weperen VYH, Khaky A, Jani NR, Kumar A and Vaseghi M. Link
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American Heart Association Scientific Sessions, 2023
Abstract 17513: Decreased Sensory Neurotransmission Due to Neuronal Mitochondrial Dysfunction Mediates Sex Differences in Vagal Remodeling After Myocardial Infarction
Devarajan A, Wang K, Lokhandwala ZA, Emamimeybodi M, Shannon K, Tompkins J and Vaseghi M. Link
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American society of Physiology, 2023
Aging Shifts the Transcriptomic Profile of Satellite Glial Cells in Murine Nodose Ganglia towards a Pro-inflammatory Phenotype
van Weperen VYH, Devarajan A, Littman R, Wang K, Shannon K, Yang X and Vaseghi M.
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American College of Cardiology Scientific Sessions, 2023
Neuropeptide Y Receptor Inhibitor Enhances Effects of Vagal Nerve Stimulation and Reduces Effects of Sympathetic Activation: Assessments using Real-Time Electrophsyiological and Myocardial Neuropeptide Measurements
Jani NR, van Weperen VYH, Emamimeybodi M, Chan CA, Hoang JD, Bal S, Smith C and Vaseghi M. Link
Circulating Norepinephrine Leads to Release of Neuropeptide Y at Cardiac Sympathetic Nerve Terminals
van Weperen VYH, Hoang JD, Jani NR, Emamimeybodi M, Bal S, Smith C and Vaseghi M. Link
Apple watch-detected ventricular tachycardia in a pregnant patient.
Ocher R, Shahid M, Sridharan A, Parikh R, Bradfield J, Vaseghi M and Shahandeh N. Link
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American Heart Association Scientific Sessions, 2022
Abstract 11494: Electrophysiological Effects of Sympathoexcitation are Mitigated by Blockade of Neuropeptide Y Y2 receptors on Cardiac Parasympathetic Nerve Terminals
van Weperen VYH, Hoang JD, Jani NR, Lokhandwala ZA, Emamimeybodi M, Chan CA, Swid MA and Vaseghi M. Link
Abstract 9547: Demographic differences in patients with frequent PVCs and cardiomyopathy in the general population receiving ambulatory holter monitoring.
Huizar JF, Sima A, Comstuck C, Kaszala K, Tan A, Frankel DS, Marchlinski F, Kowalski M, Sharma P, Gerstenfeld EP, Vaseghi M, Shivkumar K, Malo R, Morillo C and Ellenbogen KA. Link
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Heart Rhythm Scientific Sessions, 2022
The outcome spectrum for dilated cardiomyopathy and ventricular tachycardia: Results from the prospective, multicenter, DCM VT ablation study.
Zeppenfeld K, Winjnmaalen AP, Ebert M, Baldinger SH, Catto V, Vaseghi M, Arya A, Kumar S, Riva Silva M, Gaspar T, Tedrow UB, Deneke T, Soejima K, Piorkowski C, Shivkumar K, Carbucicchio C, Berruezo A, Hindricks G and Stevenson WG. Link
Effect of bilateral cardiac sympathetic denervation on exercise tolerance and cardiac function.
Tang A, Sridharan A, Sorg J, Bradfield JB, Shivkumar K and Vaseghi M. Link
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Experimental Biology Scientific Sessions, 2022
Ventricular electrophysiological effects of vagal nerve stimulation in humans with and without structural heart disease.
Hoang JD, Lokhandwala ZA, Buckley U, Krokhaleva Y, Bradfield JS, Khakpour H, Ajijola OA, Boyle NG, Shivkumar K and Vaseghi M. Link
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American Heart Association Scientific Sessions, 2021
Abstract 10597: Epidural Sympathetic Afferent Blockade by Resiniferatoxin Reverses Vagal Dysfunction Following Myocardial Infarction
Hoang JD, Swid MA, Kang K-W, Lokhandwala ZA, Chan CA, Jani NR and Vaseghi M. Link
Abstract 14090: Myocardial infarction selectively decreases cardiac vagal afferent neurotransmission: Implications for mechanisms behind cardiac parasympathetic dysfunction. Lokhandwala Z, Devarajan A, Wang K, Shannon K, Tompkins JD and Vaseghi M. Link |
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Safety Pharmacology Society Scientific Sessions, 2021
Electrocardiographic and electrophysiological effects of ranolazine and dofetilide in the anesthetized yorkshire pig.
Chan CA, Chui RW, Hoang JD, Brooks B, Vaseghi M and Engwall MJ.
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Heart Rhythm Scientific Sessions, 2020
Autonomic and Electrophysiological Effects of Thoracic Epidural Anesthesia on Infarcted Porcine Hearts - Young investigator award finalist
Hoang JD, Swid MA, Kang K-W, Chan CA and Vaseghi M Link
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American Heart Association Scientific Sessions, 2019
Abstract 13872: Quantifying the benefit of cardiac sympathetic denervation in patients with monomorphic ventricular tachycardia referred for catheter ablation: effect size analysis.
Dusi V, Gornbein J, Sorg J, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch EF, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K and Vaseghi M. Link
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International Society of Autonomic Neuroscience, 2019
Outcomes of cardiac sympathetic denervation for ventricular tachycardia: impact of urgency of presentation.
Tran K, Dusi V, Sorg N, Hoftman N, Yanagawa J, Lee JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias J, Bradfield JS, Buch EF, Fujimura OA, Boyle NG, Shivkumar K and Vaseghi M. Link
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Heart Rhythm Scientific Sessions, 2019
Neuropeptide Y Receptor (Y1) Blockade Attenuates Responses to Sympathetic Stimulation.
Hoang JD, Salavatian S, Swid MS, Kang KW and Vaseghi M. Link
Stellate Ganglion Stimulation Results in Spatiotemporal Changes of Ventricular Repolarization in Pig.
Meijborg VMF, Boukens BJ, Janse MJ, Salavatian S, Yoshie K, Opthof T, Swid MA, Hoang JD, Mistry J, Hanna P, Vaseghi M, Ajijola O, Ardell JL, Shivkumar K and Coronel R. Link
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American Heart Association Scientific Sessions, 2018
Abstract 15138: Myocardial infarction increases nociceptive cardiac neurons in the inferior vagal ganglia: implications for parasympathetic dysfunction in heart disease.
Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Armour AJ and Vaseghi M. Link
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Heart Rhythm Scientific Sessions, 2018
Left stellate ganglion stimulation causes more epicardial than endocardial shortening of repolarization in pig left ventricle.
Meijborg VMF, Boukens BJ, Janse MJ, Opthof T, Salavatian S, Yoshie K, Swid MA, Hoang J, Mistry J, Hanna P, Ajijola OA, Vaseghi M, Ardell JL, Shivkumar K and Coronel R Link
Premature ventricular contractions modulate cardiac afferent neuronal activity in the inferior vagal ganglia and alter autonomic tone: implications for tachycardia induced cardiomyopathy.
Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Smith C, Amour AJ and Vaseghi M Link
Electrocardiographic voltage velocity analysis of epicardial vs. endocardial non-ischemic ventricular tachycardia.
Shah-sayad M, Olson MD, Bradfield J, Vaseghi M, Shivkumar K and Tholakanahalli VN Link
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American Heart Association Scientific Sessions, 2017
Abstract 16967: High dose beta- blocker therapy does not overcome effects of prolonged cardiac sympathetic activation.
Yamaguchi N, Salavatian S, Ardell JL, Shivkumar K and Vaseghi M. Link
Abstract 17355: Myocardial Infarction Causes Both Structural and Functional Remodeling in Cardiac Neurons of the Inferior Vagal (Nodose) Ganglia: Implications for Mechanisms Behind Parasympathetic Withdrawal in Heart Disease
*Salavatian S, *Yamaguchi N, *Hamon D, Ardell JL, Shivkumar K and Vaseghi M. Link
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Heart Rhythm Scientific Sessions, 2017
Outcomes of catheter ablation of ventricular tachycardia by etiology in non-ischemic heart disease.
Hu T, Tung R, Vergara P, Frankel DS, Dibiase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K and Vaseghi M. Link
Hemodynamic support in catheter ablation for ventricular tachycardia: An international VT ablation center collaborative group study.
Turagram M, Vuddanda V, Jazayeri MA, Atkins D, Santangeli P, Frankel DS, Tung R, Vaseghi M, Sauer W, Nakahara S, Tzou WS, Dickfled TM, Mathuria N, Bunch J, Di Biase L, Tholakanahalli V, Tedrow UB, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE, Shivkumar K, Callans DJ, Natale A, Reddy M and Lakkireddy, DR. Link
Programmed stimulation predicts arrhythmia-free survival following ablation of non-ischemic ventricular tachycardia, An IVTCC Study.
Frankel DS, Tung R, Santangeli P, Tzou WS, Vaseghi M, Di Biase L, Nagashima K, Tedrow UB, Bunch TJ, Tholakanahalli VN, Dendi R, Reddy M, Lakkireddy DR, Vunnam R, Dickfeld TM, Weiss JP, Mathuria N, Vergara P, Patel M, Nakahara S, Vakil K, Sauer WH, Callans DJ, Natale A, Stevenson WG, Della Bella P, Shivkumar K and Marchlinski FE. Link
Outcomes of repeat ventricular tachycardia ablation in structural heart disease: An international VT ablation center collaborative study.
Tzou WS, Tung R, Frankel DS, Vaseghi M, Santangeli P, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy DR, Dickfeld TM, Weiss JP, Vergara P, Nagashima K, Vakil K, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE and Sauer WH. Link
Surgical epicardial ventricular tachycardia ablation: a large single center experience.
Hayase J, Do D, Buch EF, Macias C, Vaseghi M, Benharash P, Biniwale R, Boyle NG and Shivkumar K. Link
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American Heart Association Scientific Sessions, 2016
Value of cardiac sympathetic denervation in structural heart disease and refractory ventricular arrhythmias and predictors of outcomes: An international cardiac sympathetic denervation collaborative study (ICSDC).
Vaseghi M, Barwad P, Malavassi Corrales FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Saenz Morales, Lokhandwala Y and Shivkumar K.
Abstract 11270: Liver disease as a novel risk factor for atrial fibrillation.
Huang WA, Dunicpace E, Sorg JM and Vaseghi M. Link
Abstract 14663: Mechanisms of ventricular tachycardia recurrence and outcomes after repeat catheter ablation after cardiac sympathetic denervation in nonischemic cardiomyopathy patients.
Yu R, Vaseghi M, Ajijola OA, Tung R, Boyle NG and Shivkumar K. Link
Abstract 14711: Circannual Pattern and TEMPerature-Related Incidence of Electrical Storm: The TEMPEST Study.
Guerra F, Bonelli P, Flor M, Cipoletta L, Carbucicchio C, Izquierdo M, Kozluk E, Vaseghi M, Shivkumar K, Patani F, Cupido C, Pala S, Luiz-Granell R, Ferrero A, Tondo C and Capucci A. Link
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Heart Rhythm Scientific Sessions, 2016
Vagal nerve stimulation further reduces ventricular tachyarrhythmias that are inducible after cardiac sympathetic denervation in infarcted porcine hearts.
Yamakawa K, Rajendran PS, Irie T, Takamiya T, Hamon D, Shivkumar K and Vaseghi M. Link
The middle cervical ganglia provide direct sympathetic cardiac innervation and remodel in the setting of myocardial infarction.
Irie T, Yamakawa K, Nakamura K, Yagishita D, Shivkumar K and Vaseghi M. Link
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NIH High Risk High Reward Symposium, 2015
Infarction induce parasympathetic neural remodeling and electrical stabilization of infarct border zones by vagal nerve stimulation.
Vaseghi M, Woodward WR, Yagishita D, Rajendran PS, Hamon D, Yamakawa K, Irie T and Shivkumar K.
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Heart Rhythm Scientific Sessions, 2015
Electrophysiological effects of sympathetic activation via middle cervical ganglia are stronger than stellate ganglia and remain despite bilateral stellectomy.
Irie T, Yamakawa K, Nakamura K, Yagishita D, Hamon D, Shivkumar K and Vaseghi M. Link
Anatomical features of the LV summit and LV outflow: implications for catheter ablation of arrhythmias.
Vaseghi M, Adachi T, Felker E, Moriarty J and Shivkumar K. Link
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American College of Cardiology Scientific Sessions, 2015
Feasibility of adjunctive percutaneous epicardial mapping and ablation of atrial fibrillation: comprehensive validation of lesions set transmurality.
Tung R, Buch E, Bradfield J, Vaseghi M, Ajijola OA, Macias C, Fujimura O, Mandapati R, Boyle NG and Shivkumar K. Link
Adverse parasympathetic remodeling post myocardial infarction and electrical stabilization by vagal nerve stimulation.
Vaseghi M, Woodward WR, Yagishita D, Yamakawa K, Irie T, So EL and Shivkumar K. Link
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Heart Rhythm Scientific Sessions, 2014
Afferent vagal nerve fibers impact efferent vagal nerve response and promote heterogeneity in epicardial and endocardial repolarization.
Yamakawa K, So E, Rajendran P, Hoang J, Makkar N, Ajijola O, Zhou W, Mahajan A, Shivkumar K and Vaseghi M. Link
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American Heart Association Scientific Sessions, 2016
Abstract 18030: Electrophysiological effects of efferent and afferent right and left vagal nerve stimulation on regional ventricular myocardial repolarization.
Yamakawa K, So E, Hoang J, Makkar N, Ajijola OA, Mahajan A, Shivkumar K and Vaseghi M. Link
Abstract 16272: Intermittent vagal nerve stimulation reduces VT inducibility and dispersion of repolarization in a chronic infarct model.
Vaseghi M, Yagishita D, Yamakawa K, So E, Hoang J, Ajijola OA, Zhou W, Mahajan A and Shivkumar K. Link
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