Publications
2024
- Hoang, J. D., van Weperen, V. Y. H., Kang, K. W., Jani, N. R., Swid, M. A., Chan, C. A., Lokhandwala, Z. A., Lux, R. L., & Vaseghi, M. (2024). Antiarrhythmic Mechanisms of Epidural Blockade After Myocardial Infarction. Circulation research
- Devarajan, A., Wang, K., Lokhandwala, Z. A., Emamimeybodi, M., Shannon, K., Tompkins, J. D., Hevener, A. L., Lusis, A. J., Abel, E. D., & Vaseghi, M. (2024). Myocardial infarction causes sex-dependent dysfunction in vagal sensory glutamatergic neurotransmission that is mitigated by 17β-estradiol. JCI insight
- van Weperen VYH, Hoang JDH, Jani N, Khaky A, Herring N, Smith C, Vaseghi M. Circulating noradrenaline leads to release of neuropeptide Y from cardiac sympathetic nerve terminals via activation of β-adrenergic receptors. J. Physiol. 2024.
2023
- Dusi V, Vaseghi M. Neuronal sympathetic block for ventricular arrhythmias: one size may not fit all. Europace. 2023:25.
- van Weperen VYH, Vaseghi M. Cardiac vagal afferent neurotransmission in health and disease: review and knowledge gaps. Front. Neurosci. 2023:17.
- van Weperen VYH, Ripplinger CM, Vaseghi M. Autonomic control of ventricular function in health and disease: current state of the art. Clin Auton Res 2023:1-27.
- Sridharan A, Tang A, Sorg JM, Hoftman NN, Lee JM, Yanagawa J, Vaseghi M. Effect of Bilateral Cardiac Sympathetic Denervation on Burden of Premature Ventricular Contractions. Circ Arrhythm Electrophysiol 2023;0:e011546.
2022
- Nguyen DT, Bilchick KC, Narayan SM, Chung MK, Thomas KL, Laurita KR, Vaseghi M, Sandhu R, Chelu MG, Kannankeril PJ, Packer DL, McManus DD, Verma A, Singleton M, Tarakji K, Al-Khatib SM, Kaltman JR, Balijepalli RC, Van Hare GF, Hurwitz JL, Russo AM, Kusumoto FM, Albert CM. Opportunities and challenges in heart rhythm research: Rationale and development of an electrophysiology collaboratory. Heart rhythm. 2022:19.
- Zeppenfeld K, Wijnmaalen AP, Ebert M, Baldinger SH, Berruezo A, Catto V, Vaseghi M, Arya A, Kumar S, de Riva M, Deneke T, Gaspar T, Soejima K, van Rein N, Tedrow UB, Piorkowski C, Shivkumar K, Carbucicchio C, Hindricks G, Stevenson WG., Clinical Outcomes in Patients with Dilated Cardiomyopathy and Ventricular Tachycardia. J Am Coll Cardiol 2022;80:1045-56.
- Devarajan A, Wang K, Shannon K, Su Y, Verheyden J, Sun X & Vaseghi M. Convergent cardiorespiratory neurons represent a significant portion of cardiac and respiratory neurons in the vagal ganglia. Front Cardiovasc Med 2022.
- Tamirisa KP, Dye C, Bond RM, Hollier LM, Marinescu K, Vaseghi M, Russo AM, Gulati M, Volgman AS., Arrhythmias and heart failure in pregnancy: a dialogue on multidisciplinary collaboration. J Cardiovasc Dev Dis 2022;9: 199.
- Sridharan A, Vaseghi M., Uni vs. bi: what to do when they don’t see eye to eye. Heart Rhythm 2022; 19:1074-1075.
- Hoang JD, Yamakawa K, Rajendran P, Chan CA, Yagishita D, Nakamura K, Lux RL, Vaseghi M., Pro-Arrhythmic Effects of Sympathetic Activation are Mitigated by Vagal Nerve Stimulation in Infarcted Hearts. JACC Clin Electrophysiol 2022; 8:513-525.
- Salavatian S, Hoang JD, Yamaguchi N, Lokhandwala ZA, Swid MA, Armour JA, Ardell JL, Vaseghi M., Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia. JCI Insight 2022; 7:e155747.
- Tamirisia KP, Elkayam U, Briller JE, Mason PK, Pillarisetti K, Merchant FM, Patel H. Lakkireddy DR, Russo AM, Volgman AS, Vaseghi M., Arrhythmias in pregnancy. JACC Clin Electrophysiol 2022;8:120-135.
2021
- Dusi V, Gornbein J, Do DH, Sorg JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch E, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K, Vaseghi M., Arrhythmic risk profile and outcomes of patients undergoing cardiac sympathetic denervation for recurrent monomorphic ventricular tachycardia after ablation. J Am Heart Assoc 2021;10:e018371.
- Elliott IA, DeJesus M, Dobaria V, Vaseghi M, Ajijola OA, Shivkumar K, Hoftman NN, Benharash P, Lee JM, Yanagawa J., Minimally invasive bilateral stellate ganglionectomy for refractory ventricular tachycardia. Ann Thorac Surg 2020;29:S0003-4975(20)31902-0.
- Devarajan A, Vaseghi M., Hydroxychloroquine can potentially interfere with immune function in COVID-19 patients: Mechanisms and insights. Redox Biol 2021;38.
2020
- Wu P, Vaseghi M., The autonomic nervous system and ventricular arrhythmias in myocardial infarction and heart failure. Pacing Clin Electrophysiol 2020;43:172-180.
- Nielsen JC, Lin YJ, de Oliveira Figueiredo MJ, Sepehri Shamloo A, Alfie A, Boveda S, Dagres N, Di Toro D, Eckhardt LL, Ellenbogen K, Hardy C, Ikeda T, Jaswal A, Kaufman E, Krahn A, Kusano K, Kutyifa V, Lim HS, Lip GYH, Nava-Townsend S, Pak HN, Rodríguez Diez G, Sauer W, Saxena A, Svendsen JH, Vanegas D, Vaseghi M, Wilde A, Bunch TJ; ESC Scientific Document Group, Buxton AE, Calvimontes G, Chao TF, Eckardt L, Estner H, Gillis AM, Isa R, Kautzner J, Maury P, Moss JD, Nam GB, Olshansky B, Pava Molano LF, Pimentel M, Prabhu M, Tzou WS, Sommer P, Swampillai J, Vidal A, Deneke T, Hindricks G, Leclercq C., European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population. Europace 2020;22:1147-48 (simultaneous publication in Heart Rhythm).
- Chan SA, Vaseghi M, Kluge N, Shivkumar K, Ardell JL, Smith C., Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart. Am J Phys Heart Circ Physiol 2020;318:H1091-99.
- Hoang JD, Salavatian S, Yamaguchi N, Swid MA, David H, Vaseghi M., Cardiac Sympathetic Activation Circumvents High Dose Beta Blocker Therapy in Part Through Neuropeptide-Y Release. JCI Insight 2020; 5:e135519.
- Dusi V, Sorg. JM, Gornbein JM, Gima, Yanagawa J, Lee JM, Vecerek N, Vaseghi M, Bradfield JS, Ferrari GM, Shivkumar K, Ajijola OA., Prognostic impact of atrial rhythm and dimension in patients with structural heart disease undergoing cardiac sympathetic denervation for ventricular arrhythmias. Heart Rhythm 2020;17:714-20.
- Bradfield JS, Hayase J Liu K, Moriarty J, Kee ST, Do D, Ajijola OA, Vaseghi M, Gima J, Sorg J, Cote S, Pavez G, Buch E, Khakpour H, Krokhaleva Y, Macias C, Fujimura O, Boyle NG, Shivkumar K., Renal denervation as adjunctive therapy to cardiac sympathetic denervation for ablation of refractory ventricular tachycardia. Heart Rhythm 2020; 17:220-227.
2019
- Volgman AS, Bairey Merz CN, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Pepine CJ, Vaseghi M, Waldo AL, Wenger NK, Russo AM., Sex and Race/Ethnicity Differences in Atrial Fibrillation. J Am Coll Cardiol 2019;74:2812-15.
- Salavatian S. Yamaguchi N, Hoang J, Lin N, Patel S, Ardell JL, Armour JAA, Vaseghi M., Premature ventricular contractions activate vagal cardiac afferent neurons and alter autonomic tone: potential implication for premature ventricular contraction-induced cardiomyopathy. Am J Physiol Heart Circ Physiol 2019, 317:H607-H616.
- Krokhaleva Y, Vaseghi M., Update on prevention and treatment of sudden cardiac arrest. Trends in Cardiovasc Med 2019; 29:394-400.
2018
- Vergara P, Tzou WS, Tung R, Brombin C, Nonis A, Vaseghi M, Frankel DS, DiBiase L, Tedrow U, Mathuria N, Nakahara S, Tholakanahalli V, Bunch TJ, Weiss JP, Dickfeld T, Lakkireddy D, Burkhardt JD, Santangeli P, Callans D, Natale A, Marchlinski F, Stevenson WG, Shivkumar K, Sauer WH, Della Bella P., Predictive score for identifying survival and recurrence risk profiles in patients undergoing ventricular tachycardia ablation. Circ Arrhythm Electrophysiol 2018, 11: e006730.
- Vaseghi M, Hu TY, Tung R, Vergara P, Frankel DS, Di Biase L, Tedrow UB, Gornbein JA, Yu R, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Burkhardt DJ, Tholakanalli VN, Dickfeld TM, Weiss JP, Bunch TJ, Reddy M, Callans DJ, Lakkireddy DR, Natale A, Marchlinski FE, Stevenson WG, Della Bella P, Shivkumar K., Outcomes of catheter ablation of ventricular tachycardia based on etiology of nonischemic heart disease: An international ventricular tachycardia ablation center collaborative study. JACC Clin Electrophysiol 2018, 4:1141-1150.
- Huang WA, Dunipace MS, Sorg JM, Vaseghi M., Liver disease as a predictor of new-onset atrial fibrillation. J Am Heart Assoc 2018, 7(15): e008703.
- Kung GL, Vaseghi M, Gahm JK, Shevtsov J, Garfinkel A, Shivkumar K, Ennis DB., Microstructural infarct border zone remodeling in the post-infarct swine heart measured by diffusion tensor MRI. Front Physiol 2018; 9:826.
- Yamaguchi N, Yamakawa K, Rajendran PS, Takamiya T, Vaseghi M., Anti-arrhythmic effects of vagal nerve stimulation after cardiac sympathetic denervation in the setting of chronic myocardial infarction. Heart Rhythm 2018;15:1214-1222.
- Hoang J, Vaseghi M., A novel mechanism for regulation of cardiac Ca2+ current by estradiol: cAMPing out at the basal epicardium. Heart Rhythm 2018; 15:750-751.
- Chadda KR, Ajijola OA, Vaseghi M, Shivkumar K, Huang CL, Jeevaratnam K., Ageing, the autonomic nervous system, and arrhythmias: from brain to heart. Ageing Res Rev 2018;48: 40-50.
- Li A, Hayase J, Do D, Buch E, Vaseghi M, Ajijola OA, Macias C, Krokhaleva A, Khakpour H, Boyle NG, Benharash P, Biniwale R, Shivkumar K, Bradfield JS., Hybrid surgical vs. percutaneous access epicardial ventricular tachycardia ablation. Heart Rhythm 2018;15:512-19.
2017
- Vakil K, Garcia S. Tung R, Vaseghi M, Tedrow U, Della Bella P, Frankel DS, Vergara P, Di Biase L, Nagashima K, Nakahara S, Tzou WS, Burkhardt JD, Dickfeld T, Weiss JP, Bunch J, Callans D, Lakkireddy D, Natale A, Sauer WH, Stevenson WG, Marchlinski F, Shivkumar K, Tholakanahalli VN.. Ventricular tachycardia ablation in the elderly: An International Ventricular Tachycardia Collaborative Group analysis. Circ Arrhythm Electrophysiol 2017;10(12):e005332.
- Krokhaleva Y, Vaseghi M., How to evaluate for and manage inflammatory and infiltrative cardiomyopathies that require ventricular tachycardia ablation. Curr Cardiovasc Risk Rep 2017; 11:1-13.
- Do DH, Bradfield J, Ajijola OA, Vaseghi M, Le J, Rahman S, Mahajan A, Nogami A, Boyle NG, Shivkumar K., Thoracic epidural anesthesia can be effective for short-term management of ventricular tachycardia storm. J Am Heart Assoc 2017; 6:e007080.
- Irie T*, Yamakawa K*, Hamon D, Nakamura K, Shivkumar K, Vaseghi M., Cardiac sympathetic innervation via the middle cervical ganglia and anti-arrhythmic mechanism of bilateral stellectomy. Am J Physiol Heart Circ Physiol 2017;312:H392-H405.
- Vaseghi M, Salavatian SS, Rajendran PS, Yagishita P, Woodward WR, Hamon D, Yamakawa K, Irie T, Habecker BA, Shivkumar K., Parasympathetic dysfunction and anti-arrhythmic effect of vagal nerve stimulation following myocardial infarction. JCI Insight 2017;2 (16): e86715.
- Vaseghi M, Barwad P, Corrales Malavassi FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Saenz Morales LC, Lokhandwala Y, Shivkumar K., Cardiac sympathetic denervation for refractory ventricular arrhythmias. J Am Coll Cardiology 2017;69:3070-3080.
- Guerra F, Bonelli P, Flor M, Cipoletta L, Carbucicchio C, Izquierdo M, Kozluk E, Vaseghi M, Shivkumar K, Patani F, Cupido C, Pala S, Luiz-Granell R, Ferrero A, Tondo C, Capucci A., Circannual Pattern and TEMPerature-Related Incidence of Electrical STorm: The TEMPEST Study. Circ Arrhythm Electrophysiol 2017;10:e004634.
2016
- Saenz LC, Corrales FM, Bautista W, Traina M, Meymandi S, Rodriguez DA, Tellez LJ, Vaseghi M, Garcia F, Shivkumar K, Bradfield JS., Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease. Heart Rhythm 2016;13:138-94.
- Yamakawa K, Howard-Quijano K, Zhou W, Rajendran PS, Yagishita D, Vaseghi M, Ajijola OA, Armour JA, Shivkumar K, Ardell JL, Mahajan A., Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology. Am J Physiol Heart and Circ Physiol 2016;310:R414-21.
- Rajendran PS, Nakamura K, Ajijola OA, Vaseghi M, Amour JA, Ardell JL, Shivkumar K., Myocardial infarction induces structural and functional remodeling of the intrinsic cardiac nervous system. J Physiol 2016;594:321-41.
- Watanabe A, Seki A, Fishbein MC, Shivkumar K, Vaseghi M., Arrhythmogenic right ventricular cardiomyopathy: electroarchitecture of the substrate. Heart Rhythm Case Reports, 2016;2:47-51.
2015
- Huang WA, Shivkumar K, Vaseghi M., Device-based autonomic modulation in arrhythmia patients: the role of vagal nerves stimulation. Curr Treat Options Cardiovasc Med 2015; 17:379.
- Yamakawa K, Rajendran PS, Takamiya T, Yagishita D, So EL, Mahajan A, Shivkumar K, Vaseghi M., Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects. Am J Physiol Heart Circ Physiol 2015;309:H1579-90.
- Vaseghi M*, Tung R*, Frankel DS, Vergara P, Di Biase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K., Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study. Heart Rhythm 2015;12:1997-2007.
- Irie T, Yu R, Bradfield JS, Vaseghi M, Buch EF, Ajijola O, Macias C, Fujimura O, Mandapati R, Boyle NG, Shivkumar K, Tung R., Relationship between sinus rhythm late activation zones and critical sites of scar-related ventricular tachycardia: systematic analysis of isochronal late activation mapping. Circ Arrhythm Electrophysiol 2015; 8:390-9.
- Huang WA, Shivkumar K, Vaseghi M., Device-based autonomic modulation in arrhythmia patients: the role of vagal nerves stimulation. Curr Treat Options Cardiovasc Med 2015; 17:379.
- Mao J, Moriarty J, Mandapati R, Shivkumar K, Vaseghi M., Catheter ablation of accessory pathways near the coronary sinus, value of defining coronary arterial anatomy. Heart Rhythm 2015;12:508-14.
- Yu R, Ma S, Tung R, Stevens S, Macias C, Bradfield J, Buch E, Vaseghi M, Fujimura O, Gornbein J, Mandapati R, Shivkumar K, Boyle NG., Catheter ablation of scar-based ventricular tachycardia: relationship of procedure duration to outcomes and hospital mortality. Heart Rhythm 2015;12;86-94.
- Yagishita D, Chui RW, Yamakawa K, Rajendran PS, Ajijola OA, Nakamura K, So EL, Mahajan A, Shivkumar K, Vaseghi M., Sympathetic nerve stimulation, not circulating norepinephrine, modulated T-peak to T-end interval by increasing global dispersion of repolarization. Circ Arrhythm Electrophysiol 2015;9:174-185.
2014
- Yamakawa K, So E, Rajendran P, Hoang J, Makkar N, Mahajan A, Shivkumar K, Vaseghi M., Electrophysiological effects of right and left vagal nerve stimulation on the ventricular myocardium. Am J Physiol Heart Circ Physiol 2014;307:H722-31.
- Canan T, Vaseghi M, Girsky MJ, Yang EH., A complex rhythm treated simply: fascicular ventricular tachycardia. Am J Med 2014;127:601-04.
- Vaseghi M, Gima J, Kanaan C, Ajijola OA, Marmureanu A, Mahajan A, Shivkumar K., Cardiac sympathetic denervation in patients with refractory ventricular tachycardia or electrical storm: intermediate and long term follow up. Heart Rhythm 2014;11:360-6.
2024
- American College of Cardiology Scientific Sessions, 2024
The β1-selective blocker metoprolol does not improve vagal function in the setting of healthy or structurally diseased hearts.
van Weperen VYH, Khaky A, Jani NR, Kumar A and Vaseghi M.
2023
- American Heart Association Scientific Sessions, 2023
Abstract 17513: Decreased Sensory Neurotransmission Due to Neuronal Mitochondrial Dysfunction Mediates Sex Differences in Vagal Remodeling After Myocardial Infarction.
Devarajan A, Wang K, Lokhandwala ZA, Emamimeybodi M, Shannon K, Tompkins J and Vaseghi M. - American society of Physiology, 2023
Aging Shifts the Transcriptomic Profile of Satellite Glial Cells in Murine Nodose Ganglia towards a Pro-inflammatory Phenotype.
van Weperen VYH, Devarajan A, Littman R, Wang K, Shannon K, Yang X and Vaseghi M. - American College of Cardiology Scientific Sessions, 2023
- Neuropeptide Y Receptor Inhibitor Enhances Effects of Vagal Nerve Stimulation and Reduces Effects of Sympathetic Activation: Assessments using Real-Time Electrophsyiological and Myocardial Neuropeptide Measurements.
Jani NR, van Weperen VYH, Emamimeybodi M, Chan CA, Hoang JD, Bal S, Smith C and Vaseghi M. - Circulating Norepinephrine Leads to Release of Neuropeptide Y at Cardiac Sympathetic Nerve Terminals.
van Weperen VYH, Hoang JD, Jani NR, Emamimeybodi M, Bal S, Smith C and Vaseghi M. - Apple watch-detected ventricular tachycardia in a pregnant patient.
Ocher R, Shahid M, Sridharan A, Parikh R, Bradfield J, Vaseghi M and Shahandeh N.
- Neuropeptide Y Receptor Inhibitor Enhances Effects of Vagal Nerve Stimulation and Reduces Effects of Sympathetic Activation: Assessments using Real-Time Electrophsyiological and Myocardial Neuropeptide Measurements.
2022
- American Heart Association Scientific Sessions, 2022
- Abstract 11494: Electrophysiological Effects of Sympathoexcitation are Mitigated by Blockade of Neuropeptide Y Y2 receptors on Cardiac Parasympathetic Nerve Terminals.
van Weperen VYH, Hoang JD, Jani NR, Lokhandwala ZA, Emamimeybodi M, Chan CA, Swid MA and Vaseghi M. - Abstract 9547: Demographic differences in patients with frequent PVCs and cardiomyopathy in the general population receiving ambulatory holter monitoring.
Huizar JF, Sima A, Comstuck C, Kaszala K, Tan A, Frankel DS, Marchlinski F, Kowalski M, Sharma P, Gerstenfeld EP, Vaseghi M, Shivkumar K, Malo R, Morillo C and Ellenbogen KA.
- Abstract 11494: Electrophysiological Effects of Sympathoexcitation are Mitigated by Blockade of Neuropeptide Y Y2 receptors on Cardiac Parasympathetic Nerve Terminals.
- Heart Rhythm Scientific Sessions, 2022
- The outcome spectrum for dilated cardiomyopathy and ventricular tachycardia: Results from the prospective, multicenter, DCM VT ablation study.
Zeppenfeld K, Winjnmaalen AP, Ebert M, Baldinger SH, Catto V, Vaseghi M, Arya A, Kumar S, Riva Silva M, Gaspar T, Tedrow UB, Deneke T, Soejima K, Piorkowski C, Shivkumar K, Carbucicchio C, Berruezo A, Hindricks G and Stevenson WG. - Effect of bilateral cardiac sympathetic denervation on exercise tolerance and cardiac function.
Tang A, Sridharan A, Sorg J, Bradfield JB, Shivkumar K and Vaseghi M.
- The outcome spectrum for dilated cardiomyopathy and ventricular tachycardia: Results from the prospective, multicenter, DCM VT ablation study.
- Experimental Biology Scientific Sessions, 2022
Ventricular electrophysiological effects of vagal nerve stimulation in humans with and without structural heart disease.
Hoang JD, Lokhandwala ZA, Buckley U, Krokhaleva Y, Bradfield JS, Khakpour H, Ajijola OA, Boyle NG, Shivkumar K and Vaseghi M.
2021
- American Heart Association Scientific Sessions, 2021
- Abstract 10597: Epidural Sympathetic Afferent Blockade by Resiniferatoxin Reverses Vagal Dysfunction Following Myocardial Infarction.
Hoang JD, Swid MA, Kang K-W, Lokhandwala ZA, Chan CA, Jani NR and Vaseghi M. - Abstract 14090: Myocardial infarction selectively decreases cardiac vagal afferent neurotransmission: Implications for mechanisms behind cardiac parasympathetic dysfunction.
Lokhandwala Z, Devarajan A, Wang K, Shannon K, Tompkins JD and Vaseghi M.
- Abstract 10597: Epidural Sympathetic Afferent Blockade by Resiniferatoxin Reverses Vagal Dysfunction Following Myocardial Infarction.
- Safety Pharmacology Society Scientific Sessions, 2021
Electrocardiographic and electrophysiological effects of ranolazine and dofetilide in the anesthetized yorkshire pig.
Chan CA, Chui RW, Hoang JD, Brooks B, Vaseghi M and Engwall MJ.
2020
- Heart Rhythm Scientific Sessions, 2020
Autonomic and Electrophysiological Effects of Thoracic Epidural Anesthesia on Infarcted Porcine Hearts - Young investigator award finalist.
Hoang JD, Swid MA, Kang K-W, Chan CA and Vaseghi M.
2019
- American Heart Association Scientific Sessions, 2019
Abstract 13872: Quantifying the benefit of cardiac sympathetic denervation in patients with monomorphic ventricular tachycardia referred for catheter ablation: effect size analysis.
Dusi V, Gornbein J, Sorg J, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch EF, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K and Vaseghi M. - International Society of Autonomic Neuroscience, 2019
Outcomes of cardiac sympathetic denervation for ventricular tachycardia: impact of urgency of presentation.
Tran K, Dusi V, Sorg N, Hoftman N, Yanagawa J, Lee JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias J, Bradfield JS, Buch EF, Fujimura OA, Boyle NG, Shivkumar K and Vaseghi M. - Heart Rhythm Scientific Sessions, 2019
- Neuropeptide Y Receptor (Y1) Blockade Attenuates Responses to Sympathetic Stimulation.
Hoang JD, Salavatian S, Swid MS, Kang KW and Vaseghi M. - Stellate Ganglion Stimulation Results in Spatiotemporal Changes of Ventricular Repolarization in Pig.
Meijborg VMF, Boukens BJ, Janse MJ, Salavatian S, Yoshie K, Opthof T, Swid MA, Hoang JD, Mistry J, Hanna P, Vaseghi M, Ajijola O, Ardell JL, Shivkumar K and Coronel R.
- Neuropeptide Y Receptor (Y1) Blockade Attenuates Responses to Sympathetic Stimulation.
2018
- American Heart Association Scientific Sessions, 2018
Abstract 15138: Myocardial infarction increases nociceptive cardiac neurons in the inferior vagal ganglia: implications for parasympathetic dysfunction in heart disease.
Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Armour AJ and Vaseghi M. - Heart Rhythm Scientific Sessions, 2018
- Left stellate ganglion stimulation causes more epicardial than endocardial shortening of repolarization in pig left ventricle.
Meijborg VMF, Boukens BJ, Janse MJ, Opthof T, Salavatian S, Yoshie K, Swid MA, Hoang J, Mistry J, Hanna P, Ajijola OA, Vaseghi M, Ardell JL, Shivkumar K and Coronel R. - Premature ventricular contractions modulate cardiac afferent neuronal activity in the inferior vagal ganglia and alter autonomic tone: implications for tachycardia induced cardiomyopathy.
Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Smith C, Amour AJ and Vaseghi M. - Electrocardiographic voltage velocity analysis of epicardial vs. endocardial non-ischemic ventricular tachycardia.
Shah-sayad M, Olson MD, Bradfield J, Vaseghi M, Shivkumar K and Tholakanahalli VN.
- Left stellate ganglion stimulation causes more epicardial than endocardial shortening of repolarization in pig left ventricle.
2017
- American Heart Association Scientific Sessions, 2017
- Abstract 16967: High dose beta- blocker therapy does not overcome effects of prolonged cardiac sympathetic activation.
Yamaguchi N, Salavatian S, Ardell JL, Shivkumar K and Vaseghi M. - Abstract 17355: Myocardial Infarction Causes Both Structural and Functional Remodeling in Cardiac Neurons of the Inferior Vagal (Nodose) Ganglia: Implications for Mechanisms Behind Parasympathetic Withdrawal in Heart Disease. *Salavatian S, *Yamaguchi N, *Hamon D, Ardell JL, Shivkumar K and Vaseghi M.
- Abstract 16967: High dose beta- blocker therapy does not overcome effects of prolonged cardiac sympathetic activation.
- Heart Rhythm Scientific Sessions, 2017
- Outcomes of catheter ablation of ventricular tachycardia by etiology in non-ischemic heart disease.
Hu T, Tung R, Vergara P, Frankel DS, Dibiase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K and Vaseghi M. - Hemodynamic support in catheter ablation for ventricular tachycardia: An international VT ablation center collaborative group study.
Turagram M, Vuddanda V, Jazayeri MA, Atkins D, Santangeli P, Frankel DS, Tung R, Vaseghi M, Sauer W, Nakahara S, Tzou WS, Dickfled TM, Mathuria N, Bunch J, Di Biase L, Tholakanahalli V, Tedrow UB, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE, Shivkumar K, Callans DJ, Natale A, Reddy M and Lakkireddy, DR. - Programmed stimulation predicts arrhythmia-free survival following ablation of non-ischemic ventricular tachycardia, An IVTCC Study.
Frankel DS, Tung R, Santangeli P, Tzou WS, Vaseghi M, Di Biase L, Nagashima K, Tedrow UB, Bunch TJ, Tholakanahalli VN, Dendi R, Reddy M, Lakkireddy DR, Vunnam R, Dickfeld TM, Weiss JP, Mathuria N, Vergara P, Patel M, Nakahara S, Vakil K, Sauer WH, Callans DJ, Natale A, Stevenson WG, Della Bella P, Shivkumar K and Marchlinski FE. - Outcomes of repeat ventricular tachycardia ablation in structural heart disease: An international VT ablation center collaborative study.
Tzou WS, Tung R, Frankel DS, Vaseghi M, Santangeli P, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy DR, Dickfeld TM, Weiss JP, Vergara P, Nagashima K, Vakil K, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE and Sauer WH. - Surgical epicardial ventricular tachycardia ablation: a large single center experience.
Hayase J, Do D, Buch EF, Macias C, Vaseghi M, Benharash P, Biniwale R, Boyle NG and Shivkumar K.
- Outcomes of catheter ablation of ventricular tachycardia by etiology in non-ischemic heart disease.
2016
- American Heart Association Scientific Sessions, 2016
- Value of cardiac sympathetic denervation in structural heart disease and refractory ventricular arrhythmias and predictors of outcomes: An international cardiac sympathetic denervation collaborative study (ICSDC).
Vaseghi M, Barwad P, Malavassi Corrales FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Saenz Morales, Lokhandwala Y and Shivkumar K. - Abstract 11270: Liver disease as a novel risk factor for atrial fibrillation.
Huang WA, Dunicpace E, Sorg JM and Vaseghi M. - Abstract 14663: Mechanisms of ventricular tachycardia recurrence and outcomes after repeat catheter ablation after cardiac sympathetic denervation in nonischemic cardiomyopathy patients.
Yu R, Vaseghi M, Ajijola OA, Tung R, Boyle NG and Shivkumar K. - Abstract 14711: Circannual Pattern and TEMPerature-Related Incidence of Electrical Storm: The TEMPEST Study.
Guerra F, Bonelli P, Flor M, Cipoletta L, Carbucicchio C, Izquierdo M, Kozluk E, Vaseghi M, Shivkumar K, Patani F, Cupido C, Pala S, Luiz-Granell R, Ferrero A, Tondo C and Capucci A.
- Value of cardiac sympathetic denervation in structural heart disease and refractory ventricular arrhythmias and predictors of outcomes: An international cardiac sympathetic denervation collaborative study (ICSDC).
- Heart Rhythm Scientific Sessions, 2016
- Vagal nerve stimulation further reduces ventricular tachyarrhythmias that are inducible after cardiac sympathetic denervation in infarcted porcine hearts.
Yamakawa K, Rajendran PS, Irie T, Takamiya T, Hamon D, Shivkumar K and Vaseghi M. - The middle cervical ganglia provide direct sympathetic cardiac innervation and remodel in the setting of myocardial infarction.
Irie T, Yamakawa K, Nakamura K, Yagishita D, Shivkumar K and Vaseghi M.
- Vagal nerve stimulation further reduces ventricular tachyarrhythmias that are inducible after cardiac sympathetic denervation in infarcted porcine hearts.
- American Heart Association Scientific Sessions, 2016
- Abstract 18030: Electrophysiological effects of efferent and afferent right and left vagal nerve stimulation on regional ventricular myocardial repolarization.
Yamakawa K, So E, Hoang J, Makkar N, Ajijola OA, Mahajan A, Shivkumar K and Vaseghi M. - Abstract 16272: Intermittent vagal nerve stimulation reduces VT inducibility and dispersion of repolarization in a chronic infarct model.
Vaseghi M, Yagishita D, Yamakawa K, So E, Hoang J, Ajijola OA, Zhou W, Mahajan A and Shivkumar K.
- Abstract 18030: Electrophysiological effects of efferent and afferent right and left vagal nerve stimulation on regional ventricular myocardial repolarization.
2015
- NIH High Risk High Reward Symposium, 2015
Infarction induce parasympathetic neural remodeling and electrical stabilization of infarct border zones by vagal nerve stimulation.
Vaseghi M, Woodward WR, Yagishita D, Rajendran PS, Hamon D, Yamakawa K, Irie T and Shivkumar K. - Heart Rhythm Scientific Sessions, 2015
- Electrophysiological effects of sympathetic activation via middle cervical ganglia are stronger than stellate ganglia and remain despite bilateral stellectomy.
Irie T, Yamakawa K, Nakamura K, Yagishita D, Hamon D, Shivkumar K and Vaseghi M. - Anatomical features of the LV summit and LV outflow: implications for catheter ablation of arrhythmias.
Vaseghi M, Adachi T, Felker E, Moriarty J and Shivkumar K.
- Electrophysiological effects of sympathetic activation via middle cervical ganglia are stronger than stellate ganglia and remain despite bilateral stellectomy.
- American College of Cardiology Scientific Sessions, 2015
- Feasibility of adjunctive percutaneous epicardial mapping and ablation of atrial fibrillation: comprehensive validation of lesions set transmurality.
Tung R, Buch E, Bradfield J, Vaseghi M, Ajijola OA, Macias C, Fujimura O, Mandapati R, Boyle NG and Shivkumar K. - Adverse parasympathetic remodeling post myocardial infarction and electrical stabilization by vagal nerve stimulation.
Vaseghi M, Woodward WR, Yagishita D, Yamakawa K, Irie T, So EL and Shivkumar K.
- Feasibility of adjunctive percutaneous epicardial mapping and ablation of atrial fibrillation: comprehensive validation of lesions set transmurality.
2014
- Heart Rhythm Scientific Sessions, 2014
Afferent vagal nerve fibers impact efferent vagal nerve response and promote heterogeneity in epicardial and endocardial repolarization.
Yamakawa K, So E, Rajendran P, Hoang J, Makkar N, Ajijola O, Zhou W, Mahajan A, Shivkumar K and Vaseghi M.